US government awards Novavax $1.6 billion for coronavirus vaccine

first_imgThe addition of Novavax’s candidate to Operation Warp Speed’s portfolio “increases the odds that we will have at least one safe, effective vaccine as soon as the end of this year,” HHS Secretary Alex Azar said in a statement.Besides the massive cash infusion for Novavax, the US government inked a $450 million contract with Regeneron Pharmaceuticals Inc to make and supply its antibody cocktail for COVID-19.Novavax is somewhat of a dark horse in the race for a coronavirus vaccine. The company was not on the list of vaccine finalists for Warp Speed previously reported by the New York Times that included Moderna, AstraZeneca, Pfizer Inc, J&J and Merck & Co.In May, Novavax received an additional $388 million in funding for COVID-19 vaccine development from the Coalition for Epidemic Preparedness Innovations (CEPI), a private foundation, after a $4 million investment in March. In June, the US Defense Department awarded the company $60 million to support manufacturing of 10 million doses of its vaccine in 2020.’A big scale up’The company is in the process of transferring its vaccine technology to an unnamed contract manufacturer that has two large manufacturing facilities, its CEO said. That is in addition to the work being done by Emergent Biosolutions, which is making doses to supply the company’s smaller early and midstage clinical trials.By early next year, Novavax expects to be able to make 50 million doses a month in the United States.”It’s a big scale up in a few different manufacturing sites in the United States,” Erck said. “What it leaves us with is the capacity of making many more doses in the US in 2021.”Novavax did not start human safety trials until late May. One reason for the delay is that the vaccine is grown in insect cells, a process that can take 30 days before company scientists can start purifying it and making it in bulk.”You lose a month or so there, but I don’t think we’re behind because of our data,” Erck said, referring to animal data showing a strong immune response and high levels of virus-killing antibodies.Besides Moderna, the company trails two other candidates – one from AstraZeneca and Oxford University and one from Pfizer and BioNTech.Jefferies analyst Jared Holz said the cash infusion “places Novavax in a very enviable position should its data look compelling later in the year.”Although Novavax has not yet produced a licensed vaccine, Sanofi SA uses the same basic technology to make flu vaccine, “so the risk of us not succeeding is pretty low,” Dr. Gregory Glenn, president of research and development for Novavax, said in a telephone interview.The Novavax vaccine works in conjunction with an adjuvant – a substance that boosts the immune response to help the body build a robust defense against the virus.Currently, Novavax makes its adjuvant in Sweden. The company is building up US manufacturing capacity for its adjuvant “so that we can make upwards of a billion doses of adjuvant in the United States,” Erck said.Novavax also has a manufacturing plant in the Czech Republic and hopes to have two other plants in Europe and one in Asia, Erck said. The company is also working with a manufacturer in India. The aim there is to make more than 100 million doses a month, Erck said.Topics : “What this Warp Speed award does is it pays for production of 100 million doses, which would be delivered starting in the fourth quarter of this year, and may be completed by January or February of next year,” Novavax Chief Executive Stanley Erck told Reuters.It will also cover the cost of running a large Phase III trial, the final stage of human testing.Erck said Novavax expects results of its Phase I trial testing the vaccine’s safety within the next week or so. The company aims to start midstage trials in August or September, with Phase III testing starting in October, Erck added.The HHS announcement follows a $456 million investment in Johnson & Johnson’s vaccine candidate in March, a $486 million award to Moderna Inc in April, and up to $1.2 billion in support in May for AstraZeneca PLC’s vaccine being developed with Oxford University. The US government also awarded Emergent Biosolutions Inc $628 million to expand domestic manufacturing capacity for a potential coronavirus vaccine and drugs to treat COVID-19. The US government has awarded Novavax Inc $1.6 billion to cover testing and manufacturing of a potential vaccine for the novel coronavirus in the United States, with the aim of delivering 100 million doses by January.The award announced by the US Department of Health and Human Services is the biggest yet from “Operation Warp Speed,” the White House initiative aimed at accelerating access to vaccines and treatments to fight COVID-19, the respiratory disease caused by the coronavirus.Shares in Gaithersburg, Maryland-based Novavax rose 29% to $102 in morning trading.last_img read more

Hong Kong starts mass virus testing as China distrust swirls

first_img‘Anti China radicals’But the involvement of mainland China has sent the rumor mills into overdrive and compounded fears of Beijing’s surveillance state, which uses biometric data to monitor its citizens.Some prominent Hong Kong health experts have also questioned the efficacy of a mass testing program, arguing that more targeted monitoring of at-risk and vulnerable communities would be a better use of resources.They have also raised concerns that the act of testing so many people might itself help spread the virus in a city where emergency rules currently forbid more than two people gathering in public.A group of pro-democracy politicians and lawmakers, including prominent activist Joshua Wong, called on the public on Sunday to boycott the test. They voiced fears of mass DNA harvesting and concerns Hong Kong might introduce a mandatory health code system like those used on the mainland.Hong Kong’s government has repeatedly rejected those concerns, denying DNA would be taken and insisting that no tests would go to mainland labs.City leader Carrie Lam, a pro-Beijing appointee, slammed those opposed to the testing scheme as “active anti-Beijing, anti-government members” who “will not spare any chance to create troubles and stir up confrontations even when it comes to a public health issue”.Beijing’s Hong Kong and Macau Affairs Office called those opposed to testing “anti-China radicals” with a “vile disregard” for public health.Last week Lam also dismissed doctors who voiced concerns about the efficacy of city-wide testing as being politically motivated, angering some in the medical community.At the height of the third wave in late July, Hong Kong was recording about 150 new coronavirus cases a day.Citing the rising infections, Lam cancelled local legislature elections for a year, sparking uproar from the city’s pro-democracy camp, which had hoped to capitalize on seething public anger after last year’s huge protests.Cases have since fallen back to single digits, with just nine new infections on Monday, and government opponents have questioned why elections needed to be cancelled if the government could also conduct city-wide tests.Authorities have said mass testing is a needed emergency health measure and that it will be conducted over multiple days, unlike an election.  Topics : Hong Kong started conducting mass coronavirus tests on Tuesday, a health scheme that has been swept up in the political debate dividing the city, where many remain deeply distrustful of both local leaders and China.The voluntary tests are part of an attempt to stamp out a third wave of infections that began in late June and saw the densely populated city reimpose economically painful social distancing measures.The program has been hampered by a limited response due to the involvement of mainland Chinese testing firms and doctors — and swirling public fears of data and DNA harvesting as Beijing cracks down on the city’s democracy movement. Since registration began on Saturday, 510,000 people have signed up to take the free tests — around seven percent of the city’s 7.5 million population.More than half of all 141 community test centers across the city are fully booked for their first day on Tuesday.But health experts advising the government have said as many as five million people might need to be tested for the scheme to comprehensively uncover hidden transmissions and end the current wave.Hong Kong has recorded just over 4,800 infections since the virus first hit the city in late January but about 75 percent of those cases were detected since the start of July. Tests began at 8am (0000 GMT) on Tuesday and will run for between a week and two weeks depending on public demand, with numbers limited each day to reduce the risk of infection.Authorities have billed the scheme as a benevolent public health initiative made possible with Chinese help.last_img read more

Maryland Offshore Wind Projects Move Forward

first_imgDeepwater Wind and US Wind have notified the Maryland Public Service Commission (PSC) on their acceptance of the conditions set out by the PSC earlier this month upon approving offshore wind renewable energy credits (ORECs) to two projects to be built off the state’s coast, according to The Baltimore Sun. The two developers have thus taken a new step forward to building their offshore wind farms off Maryland, with US Wind’s project expected to be operational in January 2020 and the Skipjack offshore wind farm anticipated to be put into operation November 2022.In its order from 11 May, the PSC stated that each company must notify the Commission by 25 May whether it accepts the conditions of approval contained in the order. The PSC further added that awarding of ORECs is contingent on approval by the federal government of the developers’ site assessment plans, construction and operations plans, and other processes as required.The Commission attached nearly 30 conditions to the approval, including requirements that the developers create a minimum of 4,977 direct jobs during the development, construction and operating phases of the projects, pass 80% of any construction costs savings to ratepayers, and contribute $6 million (approx. EUR 5.4 million) each to the Maryland Offshore Wind Business Development Fund.The companies are also required to use port facilities in the greater Baltimore region and Ocean City for construction and operations and maintenance activities. The developers must invest collectively at least $76 million (approx. EUR 67.8 million) in a steel fabrication plant in Maryland and together fund at least $39.6 million (approx. EUR 35.3 million) to support port upgrades at the Tradepoint Atlantic, formerly Sparrows Point, shipyard in Baltimore County.Among the conditions is also the requirement for each developer to create opportunities for minority-owned companies to participate as investors as well as in the development and construction of the projects.last_img read more

JFSE Rolls Out New Shallow Water Tool for Middle East Market

first_imgControlled flow excavation (CFE) services expert James Fisher Subsea Excavation (JFSE) said it has developed a low draft, lightweight excavator.According to JFSE, the SP2000 ULD will primarily be used for shallow water excavation and shore pull works including trench maintenance during pull-in operations, post-trenching and backfilling.The tool, which is currently mobilising for its first project, is also capable of pipeline and cable deburial for inspection, repair and maintenance, seabed preparation, freespan correction and rock dump dispersal.The new system adds to the James Fisher’s trenching and excavation offering in the Middle East.Faisel Chaudry, Middle East regional director of JFSE, said:“We are committed to identifying solutions for our clients, using our vast experience to be innovative about the possibilities and applications of CFE.“The SP2000 ULD is an important addition to our offering in the Middle East as we continue to support new and existing clients with a range of requirements.”last_img read more


first_imgIn a recent unanimous decision, theSupreme Court En Banc stopped the implementation of the ruling of the RegionalTrial Court (RTC) in Mandaluyong City declaring two sections of MORE Power’sfranchise law void. As to the city government’s finallycollecting PECO’s long overdue realty taxes, Castro said, “It is a welcomedevelopment. We are happy. The city government now has a budget for thedelivery of services to the Ilonggos.” “With the issuance of the TRO by theSupreme Court against the Mandaluyong RTC, MORE Power is confident that the RTCin Iloilo City will take its cue and decisively rule on the Application for theIssuance of the Writ of Possession. With all due respect, the law and rules areclear: Upon compliance with the requirements, a petitioner in an expropriationcase is entitled to a writ of possession as a matter of right and it becomesthe ministerial duty of the trial court to forthwith issue the writ ofpossession,” Castro said./PN PECO failed to secure a franchise fromCongress over several issues such as poor customer relations, erroneousbillings, power failures, and high rates, etc. “Anybody who owes somebody should bepaying. Like I said two weeks ago, kun indi magbayad si PECO we are willing toparticipate in the auction,” said Castro. ILOILO City – A business permit is nota franchise and so is a provisional Certificate of Public Convenience andNecessity (CPCN), thus Panay Electric Co.’s (PECO) operation in this city istemporary at best, according to MORE Electric and Power Corp. (MORE Power)president Roel Castro. “Even if it had paid its tax dues andwould eventually be issued a business permit, the fact remains that PECO isoperating merely on the basis of a temporary CPCN. Its life is only within thetransition period,” said Castro. Under this franchise law, there is atwo-year transition period to MORE Power so as not to disrupt the powerdistribution, thus the Energy Regulatory Commission (ERC) issued PECO a CPCN. Congress instead granted MORE Power a25-year franchise to distribute electricity in the city. President RodrigoDuterte signed this legislative franchise law, Republic Act (RA) 11212, on Feb.14 this year. center_img An electrical fire flares up at a post of Panay Electric Co. near the Mandurriao public market on Friday night. Just recently, the Energy Regulatory Commission ordered PECO to correct and explain its violations of the Power Distribution Code. “The basic rule is that every law hasin its favor the presumption of constitutionality. To justify the nullificationof sections 10 and 17 of RA 11212 there must be a clear and unequivocal breachof the Constitution and not one that is doubtful, speculative orargumentative,” Castro stressed. The latest high court ruling, saidCastro, was “a manifestation of the rule of law.” The MORE Power president said his companyis “on track” to take over the power distribution system in the city. PECO questioned the franchise law atthe Mandaluyong RTC in July. It argued that sections 10 (right of eminentdomain) and 17 (transition of operations) of the franchise law wereunconstitutional. MORE Power has filed an expropriationcase against PECO at the RTC in Iloilo City but the latter was fighting it. The city government is poised to issuea business permit to PECO – whose power distribution franchise expired inJanuary this year – after the latter paid its P134.9-million real property taxdues on Dec.9 or three days before the Dec. 12 auction of P90-million worth ofits properties by the city government.last_img read more

Real Madrid snub move for Tottenham star

first_img Loading… Promoted Content7 Non-Obvious Things That Damage Your PhoneCan Playing Too Many Video Games Hurt Your Body?The Very Last Bitcoin Will Be Mined Around 2140. Read More7 Reasons It’s Better To Be A VeganYou’ve Only Seen Such Colorful Hairdos In A Handful Of Anime8 Superfoods For Growing Hair Back And Stimulating Its Growth2020 Tattoo Trends: Here’s What You’ll See This YearTop 10 Most Romantic Nations In The World20 Completely Unexpected Facts About ‘The Big Bang Theory’11 Strange Facts About Your Favorite TV Shows8 Amazing Facts About Ancient Egypt5 Of The World’s Most Unique Theme Parks Real Madrid are not interested in a move for Tottenham midfielder Dele Alli according to reports from Diario AS. Los Blancos are currently in negotiations with Jose Mourinho’s side over a double deal for Gareth Bale and Sergio Reguilon, with the former on loan and the latter on a €40m transfer. Alli was initially linked with a switch to the Spanish capital as part of the deal to bring Bale back to North London, however, Real Madrid are not considering any type of offer for the England star. One of the primary reasons for Real Madrid declining to enter negotiations for Alli, are his salary demands countering against their continued contributions to Bale’s contract.Advertisementcenter_img Read Also: Messi, Ronaldo missing from Champions League awards shortlist Rumours are starkly contradictory over how much of Bale’s salary Real Madrid will pay after his move back to the Premier League, with estimates ranging from 50% to zero. The exits of Bale and Reguilon are expected to be announced in the next 48 hours, with Real Madrid kicking off their 2020-21 La Liga defence away at Real Sociedad on September 20. FacebookTwitterWhatsAppEmail分享 last_img read more

Cricket News Australia survive Rohit Sharma blitz to win Sydney ODI by 34 runs to take lead

first_imgNew Delhi: Rohit Sharma blasted his 22nd century and MS Dhoni hit his 68th fifty. In normal situations, these contributions from India’s top batsmen would not end up in a loss. However, their disastrous start, where India were reduced to 4/3 in four overs in pursuit of 289, proved to be the difference maker as Virat Kohli’s side suffered a 34-run loss in the Sydney ODI to go 0-1 down in the three-game series on Saturday.  The gulf between the two sides was the batting. While Australia had contributions from Shaun Marsh, Usman Khawaja, Peter Handscomb and Marcus Stoinis, the Indian batting was wholly reliant on Rohit’s 133 as the rest of the batsmen contributed just 106.Aaron Finch chose to bat on an SCG wicket which was good for batting but the skipper became Bhuvneshwar Kumar’s 100th ODI victim, dragging a full back on to the stumps for 6. Alex Carey and Usman Khawaja looked to rebuild but Carey was undone in Kuldeep Yadav’s first over as the chinaman bowler got a flatter ball to bounce a bit more and Carey was cramped for the cut to edge to Rohit for 24. However, Khawaja had a good ally in Shaun Marsh and both batsmen focused on rebuilding the innings. Both batsmen found the boundaries at regular intervals and stitched a solid stand.Read More | Rohit blasts record century, becomes six-hitting machine vs AustraliaKohli tried to break the stand using many bowling combinations but the introduction of Ambati Rayudu in the attack released the pressure as Khawaja slammed two boundaries. Rayudu’s ineffective bowling was in effect a tactical blunder by Kohli who left out Kedar Jadhav, who could have bowled much better in the middle overs. Ravindra Jadeja, included in the side for Hardik Pandya, made the breakthrough with Khawaja falling for 59.Read More | After 8 years and 68 days, Peter Siddle makes an ODI comeback Peter Handscomb got going with two boundaries off Bhuvneshwar Kumar while Shaun Marsh notched up his 13th fifty by hammering two boundaries off the wayward Khaleel Ahmed. Although Kuldeep got Marsh for 54, the platform was set for Australia to notch up a big total.End overs momentumAustralia had not scored a boundary for 44 deliveries but Handscomb and Stoinis changed the momentum dramatically by slamming two sixes in the final over bowled by Kuldeep. Handscomb’s second fifty gave Australia tremendous momentum as Stoinis was also looking set. The right-hander from Victoria hammered two more boundaries off Bhuvneshwar and threated a century with a pulled six off Bhuvneshwar to long leg as Rayudu spilled the catch. However,  Handscomb carved a short ball to deep cover to hole out to Shikhar Dhawan for 73. Stoinis ended the innings in style with a blazing 47* as Australia hit 93 runs in the last 10 overs to finish on a competitive 288/5.Disaster for IndiaIn response, India had no answer to the pace of Jason Behrendorff and Jhye Richardson. Behrendorff trapped Dhawan LBW for 0 while Richardson, who began with a maiden, got the massive wicket of Kohli for 3 which was the captain’s first single digit score in 22 innings.  The previous time he was dismissed for a single digit score was 0 by Australia in the Chennai ODI of 2017. Ambati Rayudu (0) was trapped LBW by Richardson and even a review could not overturn the decision, putting India in a precarious position.Read More | MS Dhoni achieves special milestone, goes past 10,000 runs for IndiaMS Dhoni, under pressure for failing to contribute with the bat, took his time to get going. When he got an inside edge to Behrendorff, he reached 10000 runs as a keeper for India. Rohit, at the other end, slammed two sixes to keep the scoring rate healthy. After consuming 35 balls for six runs, everyone wondered what Dhoni’s approach was but he blasted a six off Nathan Lyon to signal his intentions.The 138-run stand kept India in the hunt and Dhoni notched up his 68th fifty, silencing critics for the time being. However, when he was dismissed LBW by Behrendorff for 51, replays showed that the ball pitched outside the line of leg stump but he was given out. Unfortunately, India did not have any reviews remaining as Rayudu had used up the only review of the match. Rohit, though, was not ruffled and he got closer to his century with three boundaries off Peter Siddle.With wickets tumbling at the other end and the asking rate mounting up, Rohit slammed his 22nd century and seventh against Australia. He also smashed a world record when it comes to six-hitting. His tally of six sixes took his number of sixes against Australia to 64, going past Shahid Afridi’s world record. With Rohit hitting sixes at will, it seemed India could pull off a heist but when he holed out to Glenn Maxwell off Stoinis, the end came pretty quickly.The 34-run win gives Australia a chance to seal the series in the second game in Adelaide on January 15. However, the Sydney win has given a new-look Australia, 80s retro jersey and all a fine start. For all the Latest Sports News News, Cricket News News, Download News Nation Android and iOS Mobile Apps.last_img read more

Smith praises Australia’s ‘exceptional’ bowlers

first_imgSYDNEY, Australia (AFP) – Captain Steve Smith has praised the collective efforts of his “exceptional” four front-line bowlers for contributing to Australia’s crushing 4-0 Ashes series win over England yesterday.The Australians rounded off a dominant five-match series with an innings and 123-run hammering of the beleaguered tourists on the final day of the fifth Sydney Test.Mitchell Starc, John Hazlewood, Pat Cummins and spinner Nathan Lyon all finished with 20 or more wickets in the series to take 87 in total to dominate the England batsmen.Despite this, Smith was not prepared to rate them higher than the quartet of Mitchell Johnson, Ryan Harris, Peter Siddle and Lyon who bowled Australia to a 5-0 whitewash in the last Ashes series in Australia in 2013-14.“I think all the bowlers did an exceptional job,” he told reporters.“All of our bowlers have over 20 wickets which showed that the guys have bowled together as a group, bowled in partnerships, bowled for one another and helped us take the 80-odd wickets that we’ve needed to take four Test matches.”But he stopped of declaring them a better bowling unit than their predecessors four years ago.“I think they are all great bowlers. I can’t put any of them ahead of each other,” he said.“I think both attacks were outstanding and got the job done. I can’t say any one is better than the other.”Cummins, who captured four for 39 to finish man-of-the-match in Sydney, finished as the leading wicket-taker in the series with 23 at 24.65 and played in all five Tests.Starc claimed 22 wickets at 23.54, Hazlewood 21 at 25.90 and Lyon 21 at 29.23.Lyon, the leading all-time Australian off-spinner, has now taken 290 wickets at 31.64 in 74 Tests.“Nathan has been exceptional with the way he’s bowled and the consistency he’s had has been outstanding,” Smith said.“For me the moment that changed the whole series was Nathan Lyon and his run-out (James Vince on 83) at the Gabba, that was such a huge moment in the series.“Those sort of plays can change a series and I think that was a series-changing moment.”Smith, who was the undoubted man-of-the-series with 687 runs including three centuries at 137.40, praised the entire team’s input into the triumph.“Everyone has had a role to play and had some impact on this series,” he said.“That’s what has been so special about it, it hasn’t just been one or two guys stepping up and doing the job. You can’t really win an Ashes series when that’s the case.“Looking at the series as a whole, England had their foot in the door in most Test matches.“But we just won the key moments in the games and didn’t let England back into the games, which was crucial. I was really pleased that we were able to do that.”last_img read more


first_imgThe following incidents were reported in the USC Department of Public Safety crime/incident summary between Friday, Sept. 4 and Thursday, Sept. 10.Crimes against a personAt 4:50 p.m. on Sept. 8, a student reported that her roommate, also a student, threw a bag of cleaning supplies at her chest during an argument, knocking the wind out of her. The reporting student said she feared for her safety and planned to 9:07 p.m. on Sept. 8, DPS officers responded to a student who reported that she was assaulted by her boyfriend, also a student. Officers observed that the student had a cut to her wrist and she said it occurred while her boyfriend pushed her around the bedroom during an argument. The student stated there were two previous unreported incidents in which her boyfriend burned her with a cigarette and she showed the officers scars that were consistent with her statement. The boyfriend was detained by LAPD officers, arrested and transported to the Southwest station for booking.Crimes against propertyat 11:08 a.m. on Sept. 4, Retail Unit officers monitoring surveillance cameras at Pertusati University Bookstore observed a student pick up a textbook, unwrap it and remove the online registration code before replacing the book. The officers detained the student when he exited and he was taken into custody. The student was arrested and 6:41 p.m. on Sept. 4, a student reported losing a wallet at the University Village. The wallet was subsequently turned in to lost and found and returned to the student, but all of her credit cards were missing.At 1:27 p.m. on Sept. 8, a student reported that while she was attending a dance in Marina Del Rey, a suspect removed her wallet and a camera from her purse.Miscellaneous incidentsat 4:12 p.m. on Sept. 4, a faculty member reported that a suspect threw two eggs onto the hood of his vehicle while it was parked at Parking Structure 12:19 p.m. on Sept. 4, a faculty member reported that a caller to the Elvon and Mabel Musick Law Building Center library became irate and made threatening statements when he was advised that the service he was requesting could not be provided to 3:09 p.m. on Sept. 4, a staff member reported that an audit of daily receipts from the USC University Hospital gift shop revealed irregularities that indicated possible embezzlement by another staff member. The staff member was subsequently placed on leave while an investigation is conducted.At 9:58 a.m. on Sept. 8 at USC University Hospital, a staff member reported that a hospital battery charger and four batteries were damaged, possibly after someone spilled a carbonated beverage on them.At 1:14 a.m. on Sept. 10, two students were cited to Judicial Affairs after they were discovered trespassing at McDonald’s Olympic Swim Stadium after hours.last_img read more

Salvation Army of Alpena to Host Free Summer Cookout

first_imgAddThis Sharing ButtonsShare to FacebookFacebookShare to TwitterTwitterShare to MoreAddThisThe Salvation Army of Alpena is cooking it up this summer and curbing hunger in the community with a new program.This summer Alpena’s Salvation Army will host an outdoor cookout as part of their ‘Meet Up and Eat Up Program’.With school being out, some kids are left without access to free lunches. This program aims to curb that hunger by providing free meals to children throughout the entire summer.Meals will be served from 12pm to 1pm , every Monday through Friday, until August 18th.This week, a cookout will be held and open to any and everyone in the community. The Salvation Army has been offering free meals to children from the ages of 2-18 during the summer for 8 years now.The free cookout will take place on Thursday, July 13th!For more information contact the Salvation Army of Alpena at 989–358–2769.AddThis Sharing ButtonsShare to FacebookFacebookShare to TwitterTwitterShare to MoreAddThisContinue ReadingPrevious Alpena Man Pleads Guilty to Sexually Assaulting GranddaughterNext Local Alpena Woman Celebrates a Century of Lifelast_img read more